The pope makes his first public appearance in five weeks after suffering from a serious respiratory infection.
Pope Francis left Rome's Gemelli hospital on Sunday after a five-week stay for pneumonia.
This was his first public appearance since February 14, when he was admitted due to a severe respiratory infection, which has been regarded as the most significant health challenge of his twelve-year papacy.
As he exited the hospital, Francis, 88, waved to supporters from a balcony moments before his release.
He has been relying on a wheelchair for several years and appeared with a slightly puffy face.
In a weak voice, he briefly thanked a member of the crowd who handed him yellow flowers.
The Vatican's medical team stated that although the pope has been discharged, his recovery will take considerable time, recommending an additional two months of rest at the Vatican due to his fragile health.
During his hospital stay, Francis was publicly photographed only once, with a picture released last week showing him praying in a hospital chapel.
As he got ready to leave the hospital, a convoy of police vehicles accompanied him through Rome, while hundreds of supporters gathered outside, chanting his name in encouragement.