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Sunday, Jun 01, 2025

Surge in Meningitis Cases Prompts Vaccine Expansion in France

Amid rising infections and fatalities, French health authorities recommend broader vaccination measures for meningitis.
France is witnessing a significant increase in meningitis cases, prompting government health officials to consider an expansion of vaccination efforts.

Minister of Health and Access to Care, Yannick Neuder, highlighted the urgency during a recent statement, indicating a worrying rise in meningitis infections.

The High Authority of Health (HAS) has issued new vaccination recommendations in response to this concerning trend.

Meningitis, primarily caused by bacterial infections such as meningococci, can lead to severe complications including septicemia and gastrointestinal symptoms.

The disease is known for its rapid progression and high mortality rate when untreated, along with a substantial risk of long-term health issues even after medical intervention.

In 2024, France reported over 600 cases, marking the highest incidence in two decades.

This increase has been particularly pronounced since the lifting of public health restrictions associated with the COVID-19 pandemic.

Early 2025 data suggests a continuation of this trend, with January and February figures exceeding those from the same period in 2024. Contributing factors include a severe outbreak of influenza, which has been identified as a risk factor for meningococcal infections.

Tragically, several fatalities have emphasized the importance of the situation.

Victims include a three-year-old child in Drôme and an 18-year-old female in Rennes.

These incidents have raised alarm among health professionals, underscoring the vulnerability of younger populations to this disease.

The newly proposed HAS recommendations expand on measures introduced in January, which were initially designed to address the rising prevalence of previously rare strains.

Specifically, there is notable concern regarding strains A, Y, and the particularly lethal strain W, which has largely eclipsed strain C, while B remains the predominant strain in the country.

Vaccination strategies are currently separated into two components: until 2025, a vaccine targeting B and C was administered, with the latter recently replaced by a combined A, C, W, and Y vaccine.

This latter vaccine is now mandatory for children up to one year old and is recommended for those between 11 and 14 years of age.

Under the revised guidelines, the ACWY vaccine is set to become mandatory for children up to the age of two, with calls for its immediate offering to all children under three.

Furthermore, a significant campaign is planned to address vaccination among older adolescents and young adults, specifically targeting individuals aged 15-24 who have not yet been vaccinated against meningococcal disease.

Initial vaccination drives are already underway in Rennes, following a recent fatal case.

The HAS has also reiterated its recommendations regarding the anti-B vaccine, currently mandatory for children up to age two.

New guidance urges catch-up vaccination efforts for children up to five years who have missed doses.

For older populations, the HAS's stance remains somewhat ambiguous; while it does not recommend the vaccine for adolescents due to perceived limitations in its protective duration, it proposes that the vaccine be reimbursed for all individuals aged 15-24 who seek it.

Concerns regarding the clarity and efficacy of these vaccination policies have been voiced by health experts, including infectiologist Odile Launay, who has expressed skepticism about the political will and decisiveness surrounding meningococcal vaccination campaigns.

In early March, Health authorities acknowledged the need for more coherent communication strategies to ensure public understanding of vaccination guidelines.

Minister Neuder has stated that the implementation of HAS’s primary recommendations will be expedited, aiming for an accessible message to the public.

Plans for a national campaign targeting the 15-24 age group are anticipated before the summer, alongside a coordinated school-based vaccination initiative for 11-14-year-olds starting at the beginning of the next school year, which will also include HPV vaccination.
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