Monaco Times

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Friday, Apr 04, 2025

Stefano Pessina: The Challenges Facing a Pharmaceutical Empire

Stefano Pessina, 83, navigates unprecedented challenges at Walgreens Boots Alliance as he reflects on his expansive career from Monaco.
Stefano Pessina, the 83-year-old executive chairman of Walgreens Boots Alliance (WBA), has led one of the largest pharmaceutical empires in the world from his palatial residence in Monaco, where he has lived with his wife and business partner Ornella Barra for over thirty years.

Currently, Pessina is facing one of the most challenging periods in his remarkable career, as WBA deals with unprecedented difficulties, including a significant drop in stock price, declining profitability, and store closures.

Born on June 4, 1941, in Pescara, Italy, Pessina initially pursued a degree in nuclear engineering at the Polytechnic University of Milan.

He began his career in academia before moving to the market research firm ACNielsen.

In the mid-1970s, amid socio-political turmoil in Italy, Pessina chose to take over the struggling family pharmaceutical distribution business in Naples.

He successfully restructured the company, acquiring several Italian pharmaceutical distributors and ultimately forming Alleanza Salute Italia, which became Italy's leading pharmaceutical distributor.

A pivotal moment in his career occurred when he met Ornella Barra, who also led a pharmaceutical wholesale business.

The two combined their companies, and thus began a partnership both in business and personal life, which continues to thrive over four decades later.

Under their joint leadership, the company expanded aggressively, establishing itself as a European leader in the pharmaceutical distribution sector by the early 1990s.

In 1997, the Franco-Italian group merged with British Unichem, enhancing its reach and allowing for the acquisition of approximately 500 pharmacies in the UK. A major growth phase followed when they merged with Boots Group PLC in 2006 to form Alliance Boots.

Pessina led the acquisition to take the company private, marking it as the largest leveraged buyout in the UK at that time.

In 2012, Alliance Boots announced a merger with Walgreens, the leading drugstore chain in the United States, culminating in a partnership that employed over 330,000 people across 12,500 retail locations.

The merger propelled Walgreens Boots Alliance toward impressive revenue, nearing $140 billion in 2023.

Throughout their tenure in Monaco since 1992, Pessina and Barra have managed their vast business empire while contributing to various philanthropic efforts, such as supporting cancer research through the European Organisation for Research and Treatment of Cancer (EORTC).

Despite their financial success, they maintain a focus on social responsibility and environmental initiatives, advancing sustainability within their product offerings.

However, as of 2023, WBA faces significant challenges, including a nearly one-third drop in stock price and a drastic decline in Pessina's stake value, which plummeted from $3.7 billion to $1.3 billion in one year.

Pessina’s personal wealth has been reevaluated to $6.4 billion, a stark contrast to $15.4 billion in 2015. Despite these setbacks, he remains one of the wealthiest Italians, positioned third on the list of Italy’s richest individuals.

Facing pressures from changing market dynamics, including competition from online retailers like Amazon, Pessina is reportedly reassessing WBA's growth strategy.

Recent initiatives have included the sale of wholesale and distribution segments and the closure of over a thousand stores in the U.S. A new CEO, Tim Wentworth, has initiated a cost-cutting plan while Pessina advocates for a more regionally focused business model, aligning with traditional practices.

With a commitment to innovation, Pessina suggests that WBA must now prioritize known and reliable geographic markets, adapting to current trends in the pharmaceutical industry.

The duo’s operational base in Monaco facilitates their international business engagements while allowing them to reflect on their extensive journey within the pharmaceutical landscape.
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